Speed runs for cancer research. Seriously check this stuff out. If you choose to donate, your dollars enter you in various drawings and determine various runs (like which ending to take). Proceeds go to the Cancer Prevention Foundation.
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Update for those interested. Today they broke their goal of $500,000. They're at $580,000 raised at time of comment, and they're now shooting for $750K.
That's really awesome.
It's wrapped up. Over $1,000,000 raised.
Whoa.